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Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
A number of antiemetics are effective and safe in pregnancy including: pyridoxine/doxylamine, antihistamines (such as diphenhydramine), and phenothiazines (such as promethazine). [46] With respect to effectiveness, it is unknown if one is superior to another for relieving nausea or vomiting. [46]
Morning sickness, also called nausea and vomiting of pregnancy (NVP), is a symptom of pregnancy that involves nausea or vomiting. [1] Despite the name, nausea or vomiting can occur at any time during the day. [2] Typically the symptoms occur between the 4th and 16th weeks of pregnancy. [2]
Doxylamine; Orphenadrine; Bromazine; Clemastine; Dimenhydrinate; Alkylamines: The isomerism is a significant factor in the activity of the agents in this group. E-triprolidine, for example, is 1000-fold more potent than Z-triprolidine. This difference relates to the positioning and fit of the molecules in the histamine H 1-receptor binding site ...
While most people typically carry about 10 to 15% visceral fat, having more than that can significantly increase the risk of chronic health conditions like heart disease, diabetes and even cancer.
Danielle Fishel is sharing an update about her health, saying she has completed “active cancer treatment” following her announcement in August that she was diagnosed with DCIS, ...
The observational interpretation fallacy is the cognitive bias where association identified in observational studies are misinterpreted as causal relationships.This misinterpretation often influences clinical guidelines, public health policies, and medical practices, sometimes to the detriment of patient safety and resource allocation.
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