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for skin or eye irritation if: the "corrosion" pictogram also appears; the "health hazard" pictogram is used to indicate respiratory sensitization; GHS07: Health Hazard/Hazardous to Ozone Layer Respiratory sensitization, category 1; Germ cell mutagenicity, categories 1A, 1B, 2; Carcinogenicity, categories 1A, 1B, 2; Reproductive toxicity ...
Substances are assigned to one of the five toxicity categories on the basis of LD 50 (oral, dermal) or LC 50 (inhalation). Skin corrosion means the production of irreversible damage to the skin following the application of a test substance for up to 4 hours. Substances and mixtures in this hazard class are assigned to a single harmonized ...
A corrosive material is a liquid or solid that causes full thickness destruction of human skin at the site of contact within a specified period of time. A liquid that has a severe corrosion rate on steel or aluminum based on the criteria in 49CFR 173.137(c)(2) is also a corrosive material.
Fatal in contact with skin H310+H330: Fatal in contact with skin or if inhaled H311: Toxic in contact with skin H311+H331: Toxic in contact with skin or if inhaled H312: Harmful in contact with skin H312+H332: Harmful in contact with skin or if inhaled H313: May be harmful in contact with skin H313+H333: May be harmful in contact with skin or ...
The federal Hazardous Products Act and associated Controlled Products Regulations, administered by the Workplace Hazardous Materials Bureau residing in the federal Department of Health Canada, [citation needed] established the national standard for chemical classification and hazard communication in Canada and is the foundation for the workers' "right-to-know" legislation enacted in each of ...
In Vitro Membrane Barrier Test Method for Skin Corrosion 436: Acute Inhalation Toxicity – Acute Toxic Class Method 437: Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 438
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Defatting is caused by the exposure of human skin to a chemical substance, including alcohols, detergents, chemical solvents and motor oil. Aliphatic compounds (commonly found in kerosene) cause defatting action, with lower-boiling point aliphatics having the greatest defatting action and therefore the most potential to cause dermatitis.