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Head & Shoulders (H&S) is an American brand of anti-dandruff and non-dandruff shampoo produced by parent company Procter & Gamble. The active anti-fungal ingredient in Head & Shoulders is piroctone olamine [2] or zinc pyrithione, [3] with some "clinical strength" varieties also containing selenium disulfide. [2] [3]
Selsun Blue is an over-the-counter brand of dandruff shampoo now owned by Sanofi.First made by Abbott Laboratories, the brand was bought by Chattem in 2002. Chattem was acquired by Sanofi in 2010, although in some markets, it is sold by Rohto Pharmaceutical instead.
Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. [16] A study from 2011 showed that antifungal effects of Zinc pyrithione work by copper toxicity mechanism that targets critical iron–sulphur proteins .
Head & Shoulders is a classic for a reason. A tried and true anti-dandruff shampoo, people with dry, itchy scalps rave about it. This particular product in the head and shoulders range is enriched ...
While this species does occur naturally on the skin surface of people both with and without dandruff, in 2007, it was discovered that the responsible agent is a scalp specific fungus, Malassezia globosa, [19] that metabolizes triglycerides present in sebum by the expression of lipase, resulting in a lipid byproduct: oleic acid.
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