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  2. Platform trial - Wikipedia

    en.wikipedia.org/wiki/Platform_trial

    Platform trials can be a superior design compared to simple 2-arm clinical trials when multiple therapies need investigation, because it only requires a single control group. This means that platform trials can be conducted with fewer enrolled patients than a set of potentially redundant control groups in a series of separate 2-arm trials.

  3. Multicenter trial - Wikipedia

    en.wikipedia.org/wiki/Multicenter_trial

    A multicenter research trial is a clinical trial that involves more than one independent medical institutions in enrolling and following trial participants. [1] In multicenter trials the participant institutions follow a common treatment protocol and follow the same data collection guidelines, and there is a single coordinating center that receives, processes and analyzes study data.

  4. N of 1 trial - Wikipedia

    en.wikipedia.org/wiki/N_of_1_trial

    A trial in which random allocation is used to determine the order in which an experimental and a control intervention are given to a single patient is an N of 1 randomized controlled trial. Some N of 1 trials involve randomized assignment and blinding, but the order of experimental and control interventions can also be fixed by the researcher. [2]

  5. Randomized controlled trial - Wikipedia

    en.wikipedia.org/wiki/Randomized_controlled_trial

    A randomized controlled trial (or randomized control trial; [2] RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices , diagnostic procedures , diets or other medical treatments.

  6. Drive-thru dinner: 29 fast-food restaurants open on Thanksgiving

    www.aol.com/drive-thru-dinner-29-fast-193416322.html

    To check local hours, visit the company’s website. Scooter’s Coffee . Many Scooter’s Coffee locations will be open on Thanksgiving, with hours varying. To verify local hours, check the chain ...

  7. Philadelphia man who did 24 years for murder conviction that ...

    www.aol.com/philadelphia-man-did-24-years...

    A Philadelphia man who was given a $4.1 million settlement after serving 24 years in prison for a murder conviction that was scrapped confessed to a separate killing -- over a paltry $1,200 drug debt.

  8. Mbappé and Bellingham respond to unhappy fans with goals in ...

    www.aol.com/mbapp-bellingham-respond-unhappy...

    Kylian Mbappé made some peace with Real Madrid’s fans. Mbappé scored in Madrid's 2-0 win over Getafe in the Spanish league on Sunday to help ease the pressure on the France star. Mbappé, who ...

  9. Adaptive design (medicine) - Wikipedia

    en.wikipedia.org/wiki/Adaptive_design_(medicine)

    This is in contrast to traditional single-arm (i.e. non-randomized) clinical trials or randomized clinical trials (RCTs) that are static in their protocol and do not modify any parameters until the trial is completed. The adaptation process takes place at certain points in the trial, prescribed in the trial protocol.