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  2. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan .

  3. Sacubitril - Wikipedia

    en.wikipedia.org/wiki/Sacubitril

    Sacubitril (/ s ə ˈ k juː b ɪ t r ɪ l /; INN) is an antihypertensive drug used in combination with valsartan.The combination drug sacubitril/valsartan, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. [1]

  4. Numerous factors can cause kidney disease. Here are the ... - AOL

    www.aol.com/numerous-factors-cause-kidney...

    AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...

  5. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs). It is a reasonable initial treatment for high blood pressure. [8] It is taken by mouth. [8]

  6. How much does Entresto cost with Medicare? - AOL

    www.aol.com/much-does-entresto-cost-medicare...

    Entresto helps manage chronic heart failure by reducing the effort necessary for the heart to pump blood around the body. This article explains how much a person with Medicare Part D typically ...

  7. Using some heartburn drugs may increase your risk of kidney ...

    www.aol.com/news/2016-04-15-using-some-heartburn...

    The drugs are called proton pump inhibitors, or PPIs, and you might even have one or two in your medicine cabinet right now.

  8. Neprilysin - Wikipedia

    en.wikipedia.org/wiki/Neprilysin

    It also degrades the amyloid beta peptide whose abnormal folding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein , the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface.

  9. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Drug-induced glomerular disease is not common but there are a few drugs that have been implicated. Glomerular lesions occur primarily through immune-mediated pathways rather than through direct drug toxicity. Heroin and Pamidronate are known to cause focal segmental glomerulosclerosis; Gold salts therapy can cause membranous nephropathy [4 ...

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