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  2. Respiratory compensation - Wikipedia

    en.wikipedia.org/wiki/Respiratory_compensation

    The amount of respiratory compensation in metabolic acidosis can be estimated using Winters' formula. [2] Hyperventilation due to the compensation for metabolic acidosis persists for 24 to 48 hours after correction of the acidosis, and can lead to respiratory alkalosis. [3] This compensation process can occur within minutes. [4]

  3. Winters's formula - Wikipedia

    en.wikipedia.org/wiki/Winters's_formula

    It is slower than the initial bicarbonate buffer system in the blood, but faster than renal compensation. Respiratory compensation usually begins within minutes to hours, but alone will not completely return arterial pH to a normal value (7.4). Winter's Formula quantifies the amount of respiratory compensation during metabolic acidosis. [8]

  4. Davenport diagram - Wikipedia

    en.wikipedia.org/wiki/Davenport_diagram

    Recall that the relationship represented in a Davenport diagram is a relationship between three variables: P CO 2, bicarbonate concentration and pH.Thus, Fig. 7 can be thought of as a topographical map—that is, a two-dimensional representation of a three-dimensional surface—where each isopleth indicates a different partial pressure or “altitude.”

  5. Base excess - Wikipedia

    en.wikipedia.org/wiki/Base_excess

    metabolic acidosis, or respiratory alkalosis with renal compensation if too low (less than −2 mEq/L) Blood pH is determined by both a metabolic component, measured by base excess, and a respiratory component, measured by PaCO 2 (partial pressure of carbon dioxide). Often a disturbance in one triggers a partial compensation in the other.

  6. Respiratory acidosis - Wikipedia

    en.wikipedia.org/wiki/Respiratory_acidosis

    Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...

  7. Alveolar gas equation - Wikipedia

    en.wikipedia.org/wiki/Alveolar_gas_equation

    Free interactive model of the simplified and complete versions of the alveolar gas equation (AGE) Formula at ucsf.edu; S. Cruickshank, N. Hirschauer: The alveolar gas equation in Continuing Education in Anaesthesia, Critical Care & Pain, Volume 4 Number 1 2004; Online Alveolar Gas Equation and iPhone application by Medfixation.

  8. Metabolic alkalosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_alkalosis

    Metabolic alkalosis is an acid-base disorder in which the pH of tissue is elevated beyond the normal range (7.35–7.45). This is the result of decreased hydrogen ion concentration, leading to increased bicarbonate (HCO − 3), or alternatively a direct result of increased bicarbonate concentrations.

  9. Ventilatory threshold - Wikipedia

    en.wikipedia.org/wiki/Ventilatory_threshold

    Ventilation Curve – Plot VE vs. VO 2 or Watts or Time – The point at which there is a non‐linear increase in ventilation; V‐Slope Method – Plot VO 2 vs. VCO 2 – The point at which the increase in VCO 2 is greater than the increase in VO 2