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Vagus nerve stimulation (VNS) is a medical treatment that involves delivering electrical impulses to the vagus nerve. It is used as an add-on treatment for certain types of intractable epilepsy , cluster headaches, treatment-resistant depression and stroke rehabilitation.
A vagal maneuver is an action used to stimulate the parasympathetic nervous system by activating the vagus nerve.The vagus nerve is the longest nerve of the autonomic nervous system and helps regulate many critical aspects of human physiology, including heart rate, blood pressure, sweating, and digestion through the release of acetylcholine.
Vagus nerve stimulation therapy improved the symptoms of treatment-resistant depression for nearly 500 participants in a major clinical trial.
Joseph signed on and began using a non-invasive VNS device that delivers electrical stimulation to the vagus nerve through the ear, twice a day for 10 minutes at a time.
Measurements of vagal tone can be performed by means of either invasive or noninvasive procedures. Invasive procedures are in the minority and include vagus nerve stimulation by specific manual, breathing or electrical techniques. Noninvasive techniques mainly rely on the investigation of heart rate and heart rate variability. [4] [5] [6]
Knocking out vagal nerve receptors has been shown to cause hyperphagia (greatly increased food intake). [10] Neuroscientist Ivan De Araujo and colleagues have shown that the vagus nerve transmits reward signals from the body to the brain, [11] [12] potentially explaining how stimulation of the nerve leads to emotional changes.
Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation, transcranial electric stimulation such as tDCS or tACS).
The stimulation of the mechanical receptors located in the gastric mucosa stimulates the vagus afferents. The completion of the reflex circuit by vagus efferents leads to the stimulation of postganglionic muscarinic nerves. These nerves release acetylcholine to stimulate two end effects.
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