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In cases of severe TCA overdose that are refractory to conventional therapy, intravenous lipid emulsion therapy has been reported to improve signs and symptoms in moribund patients with toxicities involving several types of lipophilic substances, therefore lipids may have a role in treating severe cases of refractory TCA overdose. [15]
Treatment of TCA overdose depends on severity of symptoms: Initially, gastric decontamination of the patient is achieved by administering, either orally or via a nasogastric tube , activated charcoal pre-mixed with water, which adsorbs the drug in the gastrointestinal tract (most useful if given within 2 hours of drug ingestion).
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
Women may be more likely to die after a heart attack than men of a similar age, new research suggests. Here are the symptoms of heart attacks women should know about.
Between working, childcare, and yes, even scheduling doctor’s appointments for spouses and parents, that fatigue or pesky jaw pain is simply brushed off by many women. And while many symptoms ...
Imipramine is a tertiary TCA, and is a potent inhibitor of serotonin reuptake, and to a greater extent than secondary amine TCAs such as nortriptyline and despiramine. [45] Norepinephrine: strong reuptake inhibition. Desipramine has more affinity to norepinephrine transporter than imipramine. Dopamine: imipramine blocks D 2 receptors. [46]
A 29-year-old man’s debilitating night terrors were the first sign of rare autoimmune disorder that rapidly progressed, landing him in the intensive care unit in a “catatonic state.” Ben ...
Traumatic cardiac arrest (TCA) is a condition in which the heart has ceased to beat due to blunt or penetrating trauma, such as a stab wound to the thoracic area. [1] It is a medical emergency which will always result in death without prompt advanced medical care.