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  2. Hepatic encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Hepatic_encephalopathy

    [4] [9] The symptoms of hepatic encephalopathy may also arise from other conditions, such as bleeding in the brain and seizures (both of which are more common in chronic liver disease). A CT scan of the brain may be required to exclude bleeding in the brain, and if seizure activity is suspected an electroencephalograph (EEG) study may be ...

  3. Hyperammonemia - Wikipedia

    en.wikipedia.org/wiki/Hyperammonemia

    Hyperammonemia, or high ammonia levels, is a metabolic disturbance characterised by an excess of ammonia in the blood. Severe hyperammonemia is a dangerous condition that may lead to brain injury and death. It may be primary or secondary. Ammonia is a substance that contains nitrogen. It is a product of the catabolism of protein.

  4. Debbie Shawcross - Wikipedia

    en.wikipedia.org/wiki/Debbie_Shawcross

    Shawcross investigates chronic liver disease. She is interested in understanding the immune system–gut–liver-brain axis. People who suffer from cirrhosis, a chronic disease of the liver, are likely to develop an infection that results in organ failure. However, little is known about the mechanisms that underpin this disease.

  5. Asterixis - Wikipedia

    en.wikipedia.org/wiki/Asterixis

    The inability of the liver to metabolize ammonia to urea damages the brain cells. The cause is thought to be predominantly related to abnormal ammonia metabolism. [6] Other metabolic encephalopathies (often in conjuction with drowsiness or stupor), especially in decompensated cirrhosis or acute liver failure. Kidney failure and azotemia. Wilson ...

  6. Encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Encephalopathy

    Can affect many body systems, particularly the brain and nervous system. Acute necrotizing encephalopathy, rare disease that occurs following a viral infection. Glycine encephalopathy: A genetic metabolic disorder involving excess production of glycine. Hepatic encephalopathy: Arising from advanced cirrhosis of the liver.

  7. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    Patients presenting as acute and hyperacute liver failure are at greater risk of developing cerebral edema and grade IV encephalopathy. The pathogenesis remains unclear, but is likely to be a consequence of several phenomena. There is a buildup of toxic substances like ammonia, mercaptan, serotonin and tryptophan in the brain.

  8. Fetor hepaticus - Wikipedia

    en.wikipedia.org/wiki/Fetor_hepaticus

    Dimethyl sulfide. Fetor hepaticus or foetor hepaticus (Latin, "liver stench" ("fetid liver") [1] (see spelling differences), also known as breath of the dead or hepatic foetor, is a condition seen in portal hypertension where portosystemic shunting allows thiols to pass directly into the lungs.

  9. Wilson's disease - Wikipedia

    en.wikipedia.org/wiki/Wilson's_disease

    The deranged protein metabolism leads to the accumulation of waste products, such as ammonia, in the bloodstream. When these irritate the brain, patients develop hepatic encephalopathy – a serious condition that causes confusion, coma, seizures and, finally, life-threatening swelling of the brain). [5]

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