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Drugs and other substances that have been associated with significant hepatotoxicity (liver damage). Subcategories ...
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver. It can be a side-effect , but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids , or in laboratory environments, such as carbon tetrachloride , or far more pervasively in the form of ethanol (drinking alcohol).
Hepatic veno-occlusive disease, myelosuppression, cytokine release syndrome, hypersensitivity and electrolyte anomalies. Ibritumomab tiuxetan: IV: CD20 antibody bound with the radioactive isotope, 90Y, induces radiation-dependent cell lysis. Non-Hodgkin's lymphoma and follicular lymphoma.
This potentially hepatotoxic botanical use, researchers say, is similar to the estimated number of people prescribed potentially hepatotoxic drugs such as nonsteroidal anti-inflammatory drugs ...
Hepatotoxicity. [14] Ketorolac: 1993 France, Germany, others Hemorrhage, Kidney Failure. [3] L-tryptophan: 1989 Germany, UK Eosinophilic myalgia syndrome. [3] Still sold in the US Levamisole (Ergamisol) 1999 US Still used as veterinary drug and as a human antihelminthic in many markets; listed on the WHO List of Essential Medicines.
This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including . cholestasis; necrosis; acute hepatitis and chronic hepatitis of different forms,
Prescriptions of these drugs should be discarded once expired because they can cause hepatotoxicity. It was once believed that tetracycline antibiotics impair the effectiveness of many types of hormonal contraception. Recent research has shown no significant loss of effectiveness in oral contraceptives while using most tetracyclines.