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In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. [1] This is called interference.
The Kosambi mapping function was introduced to account for the impact played by crossover interference on recombination frequency. It introduces a parameter C, representing the coefficient of coincidence, and sets it equal to 2r. For loci which are strongly linked, interference is strong; otherwise, interference decreases towards zero. [5]
Crossover interference is the term used to refer to the non-random placement of crossovers with respect to each other during meiosis.The term is attributed to Hermann Joseph Muller, who observed that one crossover "interferes with the coincident occurrence of another crossing over in the same pair of chromosomes, and I have accordingly termed this phenomenon ‘interference’."
The Annals of Human Genetics is a bimonthly peer-reviewed scientific journal covering human genetics. It was established in 1925 by Karl Pearson as the Annals of Eugenics , with as subtitle, Darwin's epigram "I have no Faith in anything short of actual measurement and the rule of three ". [ 1 ]
Genetics is a monthly scientific journal publishing investigations bearing on heredity, genetics, biochemistry and molecular biology. Genetics is published by the Genetics Society of America . It has a delayed open access policy, and makes articles available online without a subscription after 12 months have elapsed since first publication.
Today's NYT Connections puzzle for Wednesday, January 15, 2025The New York Times
In population genetics, the Hill–Robertson effect, or Hill–Robertson interference, is a phenomenon first identified by Bill Hill and Alan Robertson in 1966. [1] It provides an explanation as to why there may be an evolutionary advantage to genetic recombination .
With three weeks left in the 2024 NFL regular season, it seems likely that at least a few records will be broken. Keep an eye on these marks.