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InterProScan is a software package that allows users to scan sequences against member database signatures. Users can use this signature scanning software to functionally characterize novel nucleotide or protein sequences. [10] InterProScan is frequently used in genome projects in order to obtain a "first-pass" characterisation of the genome of ...
A profile HMM modelling a multiple sequence alignment. HMMER is a free and commonly used software package for sequence analysis written by Sean Eddy. [2] Its general usage is to identify homologous protein or nucleotide sequences, and to perform sequence alignments.
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In molecular biology, the HAMP domain (present in Histidine kinases, Adenylate cyclases, Methyl accepting proteins and Phosphatases) [1] is an approximately 50-amino acid alpha-helical region that forms a dimeric, four-helical coiled coil. [2]
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A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) [1] present at the N-terminus (or occasionally nonclassically at the C-terminus [2] or internally) of most newly synthesized proteins that are destined toward the ...
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