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It’s sold as a generic and under the brand names Propecia and Proscar. As a 5-alpha-reductase inhibitor, finasteride works by inhibiting the effects of the enzyme responsible for converting ...
In 1997, Merck was successful in obtaining FDA approval for a second indication of finasteride (1 mg) for treatment of male pattern hair loss, which was marketed under the brand name Propecia. [95] It was the first 5α-reductase inhibitor to be introduced and was followed by dutasteride in 2001. [96]
If you’re starting to lose your hair and want to stop it from getting worse, your healthcare provider may suggest using Propecia — either on its own or with a topical treatment like minoxidil.
Treatments for the various forms of hair loss have only moderate success. [14] Three medications have evidence to support their use in male pattern hair loss: finasteride, dutasteride and minoxidil. [15]
Finasteride (brand names Proscar, Propecia) inhibits the function of two of the isoenzymes (types 2 and 3) of 5α-reductase. [6] [7] It decreases circulating DHT levels by up to about 70%. [8] Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%.
Check out our range of hair loss treatments available online, including finasteride now that we’ve cleared its name. This article originally appeared on Hims.com and was syndicated by MediaFeed.org.
Finasteride (Proscar or Propecia) was the first steroidal 5α-reductase inhibitor approved by the U.S. Food and Drug Administration (USFDA). It inhibits the function of two of the isoenzymes (type II and III). [4] In human it decreases the prostatic DHT level by 70–90% and reduces the prostatic size. [1]
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