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Group of pharmaceuticals that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia. Type I (sodium channel blockers) Type Ia Ajmaline; Procainamide; Quinidine; Type Ib Lidocaine; Phenytoin; Type Ic Encainide; Flecainide; Propafenone; Type II (beta ...
Benzothiazepine calcium channel blockers belong to the benzothiazepine class of compounds and are an intermediate class between phenylalkylamine and dihydropyridines in their selectivity for vascular calcium channels. By having both cardiac depressant and vasodilator actions, benzothiazepines are able to reduce arterial pressure without ...
They are used in the treatment of hypertension. [ 2 ] Compared with certain other L -type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil ) that have significant action at the heart, the dihydropyridine calcium channel blockers lower blood pressure mainly by relaxing the smooth muscle of the blood ...
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International Nonproprietary Name
A recurring feature of 1,4-dihydropyridines is the presence of substituents at the 2- and 6-positions. Dihydropyridines are enamines, which otherwise tend to tautomerize or hydrolyze. [citation needed] The dominant reaction of dihydropyridines is their ease of oxidation.
Whether use is safe during pregnancy or breastfeeding is unclear. [2] [10] When used by people with liver problems, and in elderly individuals, doses should be reduced. [10] Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type ...
An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient. [1] INNs are intended to make communication more precise by providing a unique standard name for each active ingredient, to avoid prescribing errors. [ 2 ]
Although most compounds are referred to by their IUPAC systematic names (following IUPAC nomenclature), ...