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MRI contrast agents are contrast agents used to improve the visibility of internal body structures in magnetic resonance imaging (MRI). [1] The most commonly used compounds for contrast enhancement are gadolinium -based contrast agents (GBCAs).
In Dynamic susceptibility contrast MR imaging (DSC-MRI, or simply DSC), Gadolinium contrast agent (Gd) is injected (usually intravenously) and a time series of fast T2*-weighted images is acquired. As Gadolinium passes through the tissues, it induces a reduction of T2* in the nearby water protons; the corresponding decrease in signal intensity ...
Because of its paramagnetic properties, solutions of chelated organic gadolinium complexes are used as intravenously administered gadolinium-based MRI contrast agents in medical magnetic resonance imaging. The main uses of gadolinium, in addition to use as a contrast agent for MRI scans, are in nuclear reactors, in alloys, as a phosphor in ...
Gadolinium is used in magnetic resonance imaging as an MRI contrast agent or gadolinium-based contrast agent (GBCA). [3] In the 3+ oxidation state, the metal has seven unpaired electrons. This causes water around the contrast agent to relax quickly, enhancing the quality of the MRI scan.
Cardiac MRI does not pose any specific risks compared to other indications for imaging. [11] Gadolinium based contrast medium is frequently used in CMR and has been associated with nephrogenic systemic fibrosis, predominantly using linear compounds in patients with renal disease.
There are different techniques of Perfusion MRI, the most common being dynamic contrast-enhanced (DCE), dynamic susceptibility contrast imaging (DSC), and arterial spin labelling (ASL). [11] In DSC, Gadolinium contrast agent (Gd) is injected (usually intravenously) and a time series of fast T2*-weighted images is acquired. As Gadolinium passes ...
Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent. [2]It is usually administered as a salt of a complex of gadolinium with DTPA (diethylenetriaminepentacetate) with the chemical formula A 2 [Gd(DTPA)(H 2 O)]; when cation A is the protonated form of the amino sugar meglumine the salt goes under the name "gadopentetate dimeglumine".
Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity.
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