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In a second case, a fifty-nine-year-old man was prescribed amlodipine in order to treat his hypertension. [49] After eight years of taking the drug, he developed a loss of taste sensation and numbness in his tongue. [49] When he ran out of his medication, he decided not to obtain a refill and stopped taking amlodipine. [49]
Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]
Thus they are commonly present in many people's homes. In young children one pill may cause serious health problems and potentially death. [8] The calcium channel blocker that caused the greatest number of deaths in 2010 in the United States was verapamil. [2] This agent is believed to cause more heart problems than many of the others. [2]
If you're finding yourself wondering, Why is my throat sore? Here, doctors reveal the most common culprits—plus how to get relief quickly. 7 Reasons for a Sore Throat 1. Viral infections.
It is a combination of lisinopril an ACE inhibitor with amlodipine a calcium channel blocker. [1] It may be used when blood pressure is not well controlled with each of the two agents alone. [4] It is taken by mouth. [1] Side effects may include low blood pressure, kidney problems, liver problems, cough, and high blood potassium. [4]
Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure. [1] It is a combination of amlodipine, as the besilate, a calcium channel blocker, and benazepril, an angiotensin converting enzyme inhibitor. [1] It may be used if a single agent is not sufficient. [1]
Versions are available as the combination olmesartan/hydrochlorothiazide and olmesartan/amlodipine. [2] It is available as a prodrug, olmesartan medoxomil. Common side effects include dizziness, headaches, diarrhea, and back pain. [2] Serious side effects may include kidney problems, low blood pressure, and angioedema. [2]
Amlodipine: Grapefruit increases the available amount of the drug in the blood stream, leading to an unpredictable increase in antihypertensive effects. Anti-migraine drugs ergotamine (Cafergot, Ergomar), amitriptyline (Elavil, Endep, Vanatrip) and nimodipine (Nimotop) [61]
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