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The antidotes for ethylene glycol poisoning are ethanol and fomepizole. This antidotal treatment forms the mainstay of management of ethylene glycol poisoning. The toxicity of ethylene glycol comes from its metabolism to glycolic acid and oxalic acid. The goal of pharmacotherapy is to prevent the formation of these metabolites.
Ethylene glycol, antifreeze, is extremely toxic to dogs. It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol.
There are several causes of toxic optic neuropathy. [1] Among these are: ingestion of methanol (wood alcohol), ethylene glycol (automotive antifreeze), disulfiram (used to treat chronic alcoholism), halogenated hydroquinolones (amebicidal medications), ethambutol and isoniazid (tuberculosis treatment), and antibiotics such as linezolid and chloramphenicol as well as chloroquine and the related ...
Ethylene glycol has relatively high mammalian toxicity when ingested, roughly on par with methanol, with an oral LD Lo = 786 mg/kg for humans. [30] The major danger is due to its sweet taste, which can attract children and animals. Upon ingestion, ethylene glycol is oxidized to glycolic acid, which is, in turn, oxidized to oxalic acid, which is ...
The major cause of ethylene glycol toxicity is the accumulation of glycolic acid in the body, [18] but accumulation of calcium oxalate crystals in the kidneys can also lead to acute kidney failure. [17] In the case of DEG, calcium oxalate crystal are not deposited in the kidneys, implying that ethylene glycol is not on the DEG metabolic pathway.
Poisoning is the harmful effect which occurs when toxic substances are introduced into the body. [1] The term "poisoning" is a derivative of poison, a term describing any chemical substance that may harm or kill a living organism upon ingestion. [2] Poisoning can be brought on by swallowing, inhaling, injecting or absorbing toxins through the skin.
6. Bottled Water. While it might seem like a stretch to call the entire bottled water industry a scam … it kinda is. Most bottled water companies simply take municipal water and filter it for ...
The snacks were contaminated with ethylene glycol, probably originating from contamined propylene glycol. All products made by Bassar were recalled on the 7th of September. [113] 2024 – Applesauce products containing cinnamon were found to contain lead chromate, leading to reports of child lead poisoning across the United States. The source ...