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  2. Simple-type schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Simple-type_schizophrenia

    Simple-type schizophrenia is a sub-type of schizophrenia included in the International Classification of Diseases , [1] in which it is classified as a mental and behaviour disorder. [2] It is not included in the current Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ) or the upcoming ICD-11 , [ 3 ] effective 1 January 2022. [ 4 ]

  3. This resulted in stress (as a component of the conceptualization of psychosis) often being relegated to a natural consequence of the illness rather than its cause per se. The TN model proposed a more integrative approach to biopsychosocial formulations of schizophrenia that are consistent with multifactorial etiological models. [1]

  4. Thought blocking - Wikipedia

    en.wikipedia.org/wiki/Thought_blocking

    In schizophrenia, patients experience two types of symptoms: positive and negative. Positive symptoms include behavior added on to a person's daily functioning. For instance, delusions , hallucinations , disorganized speech, disorganized behavior and thought are all positive symptoms.

  5. Dopamine hypothesis of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Dopamine_hypothesis_of...

    The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine-receptor antagonistic effects. The ...

  6. Glutamate hypothesis of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Glutamate_hypothesis_of...

    Ketamine produces more similar symptoms (hallucinations, withdrawal) without observed permanent effects (other than ketamine tolerance). Both arylcyclohexamines have some(uM) affinity to D2 and as triple reuptake inhibitors. PCP is representative symptomatically, but does appear to cause brain structure changes seen in schizophrenia. [22]

  7. Causes of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Causes_of_schizophrenia

    The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.

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