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Zonisamide, sold under the brand name Zonegran among others, is a medication used to treat the symptoms of epilepsy and Parkinson's disease. [ 6 ] [ 7 ] Chemically it is a sulfonamide .
Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis , and chronic meningitis leading to neurologic damage.
American soldiers were issued a first-aid kit containing sulfa pills and powder and were told to sprinkle it on any open wound. [15] The sulfanilamide compound is more active in the protonated form. The drug has very low solubility and sometimes can crystallize in the kidneys, due to its first pK a of around 10.
Babies born prematurely (before 37 weeks) often exhibit less symptoms or in less severity than those born at full term (38 to 42 weeks). This is due to being exposed to the drug for a lesser period of time during pregnancy. Premature babies with NAS tend to recover at a much faster rate than a full term baby would. [4]
This includes babies and young children, older individuals and people with serious underlying medical conditions such as having kidney or heart disease and being immunocompromised.
Benzodiazepines act as a central nervous system depressant. The relative strength of each of these properties in any given benzodiazepine varies greatly and influences the indications for which it is prescribed. Long-term use can be problematic due to the development of tolerance to the anticonvulsant effects and dependency.
Most CDs charge early withdrawal penalties unless you have a no-penalty CD. The penalty can be several months’ worth of interest, and in some cases, it may even eat into your initial deposit amount.
A mom says her 6-year-old’s sore throat and swollen glands were dismissed as tonsillitis or a “bug going around” — but his symptoms were actually a sign of blood cancer, leukemia.