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  2. Cyclic peptide - Wikipedia

    en.wikipedia.org/wiki/Cyclic_peptide

    α-Amanitin Bacitracin Ciclosporin. Cyclic peptides are polypeptide chains which contain a circular sequence of bonds. [1] This can be through a connection between the amino and carboxyl ends of the peptide, for example in cyclosporin; a connection between the amino end and a side chain, for example in bacitracin; the carboxyl end and a side chain, for example in colistin; or two side chains ...

  3. Cyclotide - Wikipedia

    en.wikipedia.org/wiki/Cyclotide

    The stunting effect of kalata B1 cyclic peptide on growth and development of Helicoverpa punctigera, a caterpillar from the Lepidopteran order. [6]Cyclotides have been reported to have a wide range of biological activities, including anti-HIV, insecticidal, anti-tumour, antifouling, anti-microbial, hemolytic, neurotensin antagonism, trypsin inhibition, and uterotonic activities.

  4. Arginylglycylaspartic acid - Wikipedia

    en.wikipedia.org/wiki/Arginylglycylaspartic_acid

    These drugs block activation of the integrin responsible for aggregation of platelets (αIIbβ3, also known as glycoprotein IIb/IIIa) in response to the blood glycoproteins fibrinogen and von Willebrand factor. Eptifibatide (marketed as Integrilin) is a cyclic (circular) seven amino acid peptide, whereas tirofiban is a small molecule designed ...

  5. Category:Cyclic peptides - Wikipedia

    en.wikipedia.org/wiki/Category:Cyclic_peptides

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  6. Split-intein circular ligation of peptides and proteins

    en.wikipedia.org/wiki/Split-intein_circular...

    [3] Circular peptides tend to be resistant to protease activity, and may be suitable for use as orally administered drugs. Once a cyclic peptide is identified with a biological activity of interest, it may also be possible to identify the target of the peptide (a gene that encodes a protein with which it interacts) by functional complementation ...

  7. Diketopiperazine - Wikipedia

    en.wikipedia.org/wiki/Diketopiperazine

    DKP's are the smallest known class of cyclic peptide. [1] Despite their name, they are not ketones, but amides. Three regioisomers are possible, differing in the locations of the carbonyl groups. Retosiban [2] is a diketopiperazine being investigated as an oral drug. One isomer is an oxamide obtained from ethylenediamine.

  8. Puzzle solutions for Wednesday, Dec. 4, 2024

    www.aol.com/news/puzzle-solutions-wednesday-dec...

    He was the best singer ever." − James Darren (Distributed by Andrews McMeel) Cryptoquote. BE A RAINBOW IN SOMEONE ELSE'S CLOUD. − MAYA ANGELOU (Distributed by King Features) Cryptoquip.

  9. Ciclosporin - Wikipedia

    en.wikipedia.org/wiki/Ciclosporin

    Ciclosporin is a cyclic peptide of 11 amino acids; it contains a single D-amino acid, which is rarely encountered in nature. Unlike most peptides, ciclosporin is not synthesized by ribosomes. [44] Ciclosporin is highly metabolized in humans and animals after ingestion.