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Food protein-induced enterocolitis syndrome (FPIES) is a systemic, non IgE-mediated food allergy to a specific trigger within food, most likely food protein.As opposed to the more common IgE food allergy, which presents within seconds with rash, hives, difficulty breathing or anaphylaxis, FPIES presents with a delayed reaction where vomiting is the primary symptom.
First, the excessive bacterial concentrations can cause direct inflammation of the small bowel cells, leading to an inflammatory diarrhea. The malabsorption of lipids, proteins and carbohydrates may cause poorly digestible products to enter into the colon. This can cause an osmotic diarrhea or stimulate the colonic cells to cause a secretory ...
The damage to the gastrointestinal tract wall is caused by eosinophilic infiltration and degranulation. [15] As a part of host defense mechanism, eosinophils are normally present in gastrointestinal mucosa, though the finding in deeper tissue is almost always pathologic. [16] What triggers such dense infiltration in EG is not clear.
Pseudodiarrhea is often associated with rectal urgency and accompanies irritable bowel syndrome, hyperthyroidism, and anorectal disorders such as proctitis. Patients with rectal obstruction (e.g., from fecal impaction, obstruction due to a vaginal pessary ) may also present with pseudodiarrhea, since only liquid stool can make it through.
The signs and symptoms of protein losing enteropathy include diarrhea, fever, and general abdominal discomfort. [4] Swelling of the legs due to peripheral edema can also occur; however, if the PLE is related to a systemic disease such as congestive heart failure or constrictive pericarditis, then these symptoms could be due directly to the underlying illness. [2]
Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea.It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.
Clinical manifestations of IPEX syndrome include eczema, endocrine disorders, and autoimmune enteropathy. [27] The most prevalent endocrine disorder is type one diabetes however, adrenal insufficiency and thyroiditis are also common. [30] After one month of age, the most frequent gastrointestinal symptoms are diarrhea as well as failure to ...
Functional abdominal pain syndrome is a functional gastrointestinal disorder. [4] Functional gastrointestinal disorders (FGD) are common medical conditions characterized by recurrent and persistent gastrointestinal symptoms caused by improper functioning of the enteric system in the absence of any identifiable organic or structural pathology, such as ulcers, inflammation, tumors or masses.