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Ulixacaltamide is an investigational new drug developed by Praxis Precision Medicines, designed to treat essential tremor, [1] a common neurological disorder characterized by involuntary rhythmic shaking. It functions as a selective inhibitor of T-type calcium channels, which are implicated in the abnormal neuronal activity associated with ...
Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause. [6]
DBS is FDA approved or has FDA device exemptions for treatment of Parkinson's Disease, dystonia, essential tremor, obsessive-compulsive disorder and epilepsy. In Europe, beyond these indications, a CE mark exists for treatment of Alzheimer's disease. There was a past device exemption for OCD as well but this has not been renewed. [36]
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Essential tremor (sometimes inaccurately called benign essential tremor) is the most common of the more than 20 types of tremor. Although the tremor may be mild and nonprogressive in some people, in others, the tremor is slowly progressive, starting on one side of the body but affecting both sides within 3 years.
In 2016, Insightec obtained a PMA from the FDA to market its Exablate Neuro system to treat essential tremor, [9] and the next month published data from the pivotal trial in the New England Journal of Medicine. [10] In 2016, the company hired Maurice R. Ferré, the founder and former CEO of Mako Surgical, as its CEO. [11]
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