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  2. Phage therapy - Wikipedia

    en.wikipedia.org/wiki/Phage_therapy

    The bacterial cell causing the infection is unable to reproduce and instead produces additional phages. [4] Phages are very selective in the strains of bacteria they are effective against. [5] Advantages include reduced side effects and reduced risk of the bacterium developing resistance, since [5] bacteriophages are much more specific than ...

  3. Escherichia virus T4 - Wikipedia

    en.wikipedia.org/wiki/Escherichia_virus_T4

    Surviving T4 virus released from multicomplexes show no increase in mutation, indicating that MR of UV irradiated virus is an accurate process. [36] The bottom figure shows the survival curves for inactivation of virus T4 by the DNA damaging agent mitomycin C (MMC). In this case the survival curve for multicomplexes has no initial shoulder ...

  4. Bacteriophage - Wikipedia

    en.wikipedia.org/wiki/Bacteriophage

    Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.

  5. List of dog diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_dog_diseases

    Treatment is with oral thyroid hormone supplementation. [105] [106] Lack of enough iodine in the diet can produce a form of hypothyroidism; without the proper amount of it, the thyroid gland fails to produce enough thyroid hormone. [102] Myxedema coma is a rare but serious aspect of the disease that is a medical emergency. [107]

  6. Bedinvetmab - Wikipedia

    en.wikipedia.org/wiki/Bedinvetmab

    Half the dogs received bedinvetmab and half the dogs received a sterile saline injection every 28 days for a total of three doses. [5] Before treatment and on various days throughout the study, owners used the Canine Brief Pain Inventory (CBPI) assessment tool to measure the severity of the dog's pain and the degree to which the pain interfered ...

  7. Phage display - Wikipedia

    en.wikipedia.org/wiki/Phage_display

    Phage display cycle. 1) fusion proteins for a viral coat protein + the gene to be evolved (typically an antibody fragment) are expressed in bacteriophage. 2) the library of phage are washed over an immobilised target. 3) the remaining high-affinity binders are used to infect bacteria. 4) the genes encoding the high-affinity binders are isolated.

  8. Lytic cycle - Wikipedia

    en.wikipedia.org/wiki/Lytic_cycle

    Lysis inhibition: T4-like phages have two genes, rI and rIII, that inhibit the T4 holin, if the infected cell undergoes super-infection by another T4 (or closely related) virion. Repeated super-infection can cause the T4 infection to continue without lysis for hours, leading to accumulation of virions to levels 10-fold higher than normal.

  9. Anti-sigma factors - Wikipedia

    en.wikipedia.org/wiki/Anti-sigma_factors

    T4 bacteriophage uses anti-sigma factor to ruin the Escherichia coli polymerase in order that direct exclusive transcription of its own genes. AsiA is an anti-sigma factor gene that is required for bacteriophage T4 to be developed). Which means that AsiA is an essential anti-sigma factor in bacteriophage. [6] [4] [9] [8]

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