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In 1927, Sakel, who had recently qualified as a medical doctor in Vienna and was working in a psychiatric clinic in Berlin, began to use low (sub-coma) doses of insulin to treat drug addicts and psychopaths, and when one of the patients experienced improved mental clarity after having slipped into an accidental coma, Sakel reasoned the treatment might work for mentally ill patients. [3]
Insulin shock therapy was discontinued due to critical concerns over its safety and effectiveness. This method, which induced comas in patients through insulin injections, resulted in severe adverse effects, including hypoglycemic episodes, seizures , obesity , and in some cases, irreversible brain damage that was mistakenly regarded as ...
insulin shock therapy Manfred Joshua Sakel (June 6, 1900 – December 2, 1957) was an Austrian-Jewish (later Austrian-American ) neurophysiologist and psychiatrist , credited with developing insulin shock therapy in 1927.
William Walters Sargant (24 April 1907 – 27 August 1988) was a British psychiatrist who is remembered for the evangelical zeal with which he promoted treatments such as psychosurgery, deep sleep treatment, electroconvulsive therapy and insulin shock therapy.
Scull details the personalities and progress behind other treatments like Hydrotherapy, electrotherapy, insulin shock therapy, injections of Camphor, Metrazol, electroconvulsive or “shock” therapy, as well as frequently deadly surgical interventions such as colectomy, and lobotomy.
Glucagon is a hormone that rapidly counters the metabolic effects of insulin in the liver, causing glycogenolysis and release of glucose into the blood. It can raise the glucose by 30–100 mg/dL within minutes in any form of hypoglycemia caused by insulin excess (including all types of diabetic hypoglycemia).
Early initiation of insulin therapy for the long-term management of conditions such as type 2 diabetes would suggest that the use of insulin has unique benefits, however, with insulin therapy, there is a need to gradually raise the dose and the complexity of the regimen, as well as the likelihood of developing severe hypoglycemia which is why ...
He received three months of insulin shock therapy, which erased much of his long-term memory. [3] [9] Afterwards, his mother said that her "biggest regret in life was that she had allowed that treatment to occur". [12] In 1965, he was accepted into the University of Houston's pre-law program.