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The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of acidosis): Hyperalimentation (e.g. from TPN containing ammonium chloride) Chloride administration, often from normal saline; Acetazolamide and other carbonic anhydrase inhibitors; Renal tubular acidosis [1]
The anion gap is the quantity difference between cations (positively charged ions) and anions (negatively charged ions) in serum, plasma, or urine. The magnitude of this difference (i.e., "gap") in the serum is calculated to identify metabolic acidosis. If the gap is greater than normal, then high anion gap metabolic acidosis is diagnosed.
Result 1: if there is a normal anion gap acidosis, the (AG – 12) part of the equation will be close to zero, the delta ratio will be close to zero and there is no mixed acid–base disorder. Your calculations can stop here. A normal anion gap acidosis (NAGMA) has more to do with a change in [Cl −] or [HCO − 3] concentrations.
The mnemonic "MUDPILES" is used to remember the causes of a high anion gap. [ 1 ] M - methanol / metformin U - uremia D - diabetic ketoacidosis P - paraldehyde / propylene glycol I - Infection / ischemia / isoniazid L - lactate E - ethylene glycol / ethanol S - salicylates / starvation
Urine NH 4 + is difficult to measure directly, but its excretion is usually accompanied by the anion chloride. A negative urine anion gap can be used as evidence of increased NH 4 + excretion. In a metabolic acidosis without a serum anion gap: A positive urine anion gap suggests a low urinary NH 4 + (e.g. renal tubular acidosis).
Hyperchloremic acidosis is a form of metabolic acidosis associated with a normal anion gap, a decrease in plasma bicarbonate concentration, and an increase in plasma chloride concentration [1] (see anion gap for a fuller explanation).
A mnemonic is a memory aid used to improve long-term memory and make the process of consolidation easier. Many chemistry aspects, rules, names of compounds, sequences of elements, their reactivity, etc., can be easily and efficiently memorized with the help of mnemonics. This article contains the list of certain mnemonics in chemistry.
1 Thanks for the mnemonic! 2 Non-anion gap acidosis. ... Talk: Normal anion gap acidosis. Add languages. Page contents not supported in other languages.