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  2. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    The 81 mg tablets are commonly called "baby aspirin" or "baby-strength", because they were originally – but no longer – intended to be administered to infants and children. [167] No medical significance occurs due to the slight difference in dosage between the 75 mg and the 81 mg tablets.

  3. History of aspirin - Wikipedia

    en.wikipedia.org/wiki/History_of_aspirin

    Therefore, Bayer was limited to marketing Aspirin directly to doctors. [3]: 80–83 When production of Aspirin began in 1899, Bayer sent out small packets of the drug to doctors, pharmacists and hospitals, advising them of Aspirin's uses and encouraging them to publish about the drug's effects and effectiveness.

  4. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    One of the first advertisements for Bayer Aspirin, published in The New York Times in 1917. It is widely believed that naturally occurring salicin in willow trees and other plants was used by the ancients as a form of analgesic or anti-inflammatory drug, [156] but this story, although compelling, is not entirely true.

  5. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]

  6. Sterling Drug - Wikipedia

    en.wikipedia.org/wiki/Sterling_Drug

    Bayer was a losing bidder for the purchase of Sterling Winthrop, but in September 1994, it purchased the over the counter division of Sterling Winthrop in the US, Canada and Puerto Rico from SmithKline Beecham for $1 billion. Bayer also re-acquired the brand rights to the "Bayer Aspirin" name it had lost because of World War I. [17]

  7. Great Phenol Plot - Wikipedia

    en.wikipedia.org/wiki/Great_Phenol_Plot

    Much of the phenol would go to the German-owned Chemische Fabrik von Heyden's American subsidiary; Heyden was the supplier of Bayer's salicylic acid for aspirin manufacture. By July 1915, Edison's plants were selling about three tons of phenol per day to Schweitzer; Heyden's salicylic acid production was soon back on line, and in turn Bayer's ...

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