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2. AMP-activated protein kinase - Wikipedia

   en.wikipedia.org/wiki/AMP-activated_protein_kinase

   The activated AMPK increases muscle metabolic activity, including glycolysis, which leads to marked elevation of circulating lactate. [38] AMPK activity increases with exercise and the LKB1/MO25/STRAD complex is considered to be the major upstream AMPKK of the 5’-AMP-activated protein kinase phosphorylating the α subunit of AMPK at Thr-172.

3. PRKAB1 - Wikipedia

   en.wikipedia.org/wiki/PRKAB1

   PRKAB1 has been shown to interact with PRKAG2 [7] and PRKAG1. [7]The 5'-AMP-activated protein kinase beta subunit interaction domain (AMPKBI) is a conserved domain found in the beta subunit of the 5-AMP-activated protein kinase complex, and its yeast homologues Sip1 (SNF1-interacting protein 1), Sip2 (SNF1-interacting protein 2) and Gal83 (galactose metabolism 83), which are found in the SNF1 ...

4. Protein kinase, AMP-activated, alpha 1 - Wikipedia

   en.wikipedia.org/wiki/Protein_kinase,_AMP...

   It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects ...

5. PRKAA2 - Wikipedia

   en.wikipedia.org/wiki/PRKAA2

   AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase ( HMGCR ), key enzymes involved in regulating de novo biosynthesis of fatty acid ...

6. Adenosine monophosphate - Wikipedia

   en.wikipedia.org/wiki/Adenosine_monophosphate

   AMPK, as a cellular energy sensor, is activated by decreasing levels of ATP, which is naturally accompanied by increasing levels of ADP and AMP. [9] Though phosphorylation appears to be the main activator for AMPK, some studies suggest that AMP is an allosteric regulator as well as a direct agonist for AMPK. [10]

7. AICA ribonucleotide - Wikipedia

   en.wikipedia.org/wiki/AICA_ribonucleotide

   AICAR is an analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. The drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.