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Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Dahl's sign (also Thinker's sign or Target sign) [1] is a clinical sign in which areas of darkened (hyperpigmentation) and thickened (hyperkeratotic) skin are seen on the lower thighs and elbows. [2] It occurs in patients with longstanding severe chronic obstructive pulmonary disease. [3]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis . Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
Retinol increases cell turnover, which can lighten pigmentation. "For melasma, retinol can be used as a stand-alone topical and is also commonly prescribed as a combination cream," says Dr. Charles.
A dermatofibroma, or benign fibrous histiocytomas, is a benign nodule in the skin, typically on the legs, elbows or chest of an adult. [3] It is usually painless. [3] It usually ranges from 0.2cm to 2cm in size but larger examples have been reported. [3] It typically results from mild trauma such as an insect bite. [3]
Beauty writer Larry Stansbury tested the La Roche-Posay Mela B3 Dark Spot Serum for 12 weeks. Here, see his results and read his final thoughts.
These are the best products for hyperpigmentation—tested by editors, dermatologists, and experts—to help get rid of acne scars, melasma, and sun spots.
Poikiloderma vasculare atrophicans (PVA), is a cutaneous condition (skin disease) characterized by hypo- or hyperpigmentation (diminished or heightened skin pigmentation, respectively), telangiectasia and skin atrophy. [3] [4] [5] Other names for the condition include prereticulotic poikiloderma and atrophic parapsoriasis. [6]
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