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For example, in clinical trials, the drug strontium ranelate was found to aid bone growth, increase bone density, and lessen vertebral, peripheral, and hip fractures in women. Strontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption, resulting in a rebalance of bone turnover in favor of ...
A bone seeker is an element, often a radioisotope, that tends to accumulate in the bones of humans and other animals when introduced into the body.. For example, strontium and radium are chemically similar to calcium and can replace the calcium in bones.
The former has a half-life of 50.6 days and is used to treat bone cancer due to strontium's chemical similarity and hence ability to replace calcium. [23] [24] While 90 Sr (half-life 28.90 years) has been used similarly, it is also an isotope of concern in fallout from nuclear weapons and nuclear accidents due to its production as a fission ...
As strontium is water-soluble, the perovskite form strontium titanate is usually employed as it is not water-soluble and has a high melting point. [ 2 ] Strontium-89 is a short-lived beta emitter which has been used as a treatment for bone tumors , this is used in palliative care in terminal cancer cases.
Strontium is naturally deposited in hydroxyapatite, the mineral component of bones and teeth, following its consumption in food and water. [11] Each locale has a unique Sr isotope ratio and, therefore, the ratio found in a bone or enamel sample can be cross referenced against a record of environmental Sr ratios and assigned to a region. [ 11 ]
Strontium belongs to the same periodic family as calcium (alkaline earth metals), and is metabolised in a similar fashion, preferentially targeting metabolically active regions of the bone. 89 Sr is an artificial radioisotope used in the treatment of osseous (bony) metastases of bone cancer .
Naturally occurring strontium is nonradioactive and nontoxic at levels normally found in the environment, but 90 Sr is a radiation hazard. [4] 90 Sr undergoes β − decay with a half-life of 28.79 years and a decay energy of 0.546 MeV distributed to an electron, an antineutrino, and the yttrium isotope 90 Y, which in turn undergoes β − decay with a half-life of 64 hours and a decay energy ...
All other strontium isotopes have half-lives shorter than 50 days, most under 100 minutes. Strontium-89 is an artificial radioisotope used in treatment of bone cancer; [ 5 ] this application utilizes its chemical similarity to calcium, which allows it to substitute calcium in bone structures.
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