Search results
Results from the WOW.Com Content Network
Similarly, the four known classes of hemoglobins (hemoglobin A, hemoglobin A2, hemoglobin B, and hemoglobin F) are paralogs of each other. While each of these proteins serves the same basic function of oxygen transport, they have already diverged slightly in function: fetal hemoglobin (hemoglobin F) has a higher affinity for oxygen than adult ...
The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [41] Homologous sequences are paralogous if they were created by a duplication event within the genome. For gene duplication events, if a gene in an organism is duplicated, the two copies are paralogous. They can shape the structure of whole genomes and thus ...
Some basic conventions, such as (1) that animal/human homolog (ortholog) pairs differ in letter case (title case and all caps, respectively) and (2) that the symbol is italicized when referring to the gene but nonitalic when referring to the protein, are often not followed by contributors to medical journals.
6469 20423 Ensembl ENSG00000164690 ENSMUSG00000002633 UniProt Q15465 Q62226 RefSeq (mRNA) NM_000193 NM_001310462 NM_009170 RefSeq (protein) NP_000184 NP_001297391 NP_033196 Location (UCSC) Chr 7: 155.8 – 155.81 Mb Chr 5: 28.66 – 28.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sonic hedgehog protein (SHH) is encoded for by the SHH gene. The protein is named after the video ...
69627 Ensembl ENSG00000182118 ENSMUSG00000043068 UniProt Q96GI7 Q14BJ1 RefSeq (mRNA) NM_198552 NM_001081120 RefSeq (protein) NP_940954 NP_001074589 Location (UCSC) Chr 1: 231.02 – 231.04 Mb Chr 8: 125.47 – 125.48 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein FAM89A (family with sequence similarity 89, member A) is a protein which in humans is encoded by the FAM89A gene ...
Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
The search engine that helps you find exactly what you're looking for. Find the most relevant information, video, images, and answers from all across the Web.
Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. [5] [6] LIN28 encodes an RNA-binding protein [7] that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA. [8] Lin28 binds to the let-7 pre-microRNA and blocks production of the mature let-7 microRNA in mouse embryonic stem cells.