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  2. Sirtuin 4 - Wikipedia

    en.wikipedia.org/wiki/Sirtuin_4

    SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. [7] A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty acid oxidation in muscle and liver cells.

  3. Sirtuin - Wikipedia

    en.wikipedia.org/wiki/Sirtuin

    SIRT6 is a chromatin-associated protein and in mammalian cells is required for base excision repair of DNA damage. [30] SIRT6 deficiency in mice leads to a degenerative aging-like phenotype. [ 30 ] In addition, SIRT6 promotes the repair of DNA double-strand breaks. [ 31 ]

  4. Serine - Wikipedia

    en.wikipedia.org/wiki/Serine

    Had D amino acids been discovered in humans sooner, the glycine site on the NMDA receptor might instead be named the D-serine site. [19] Apart from central nervous system, D -serine plays a signaling role in peripheral tissues and organs such as cartilage, [ 20 ] kidney, [ 21 ] and corpus cavernosum.

  5. Glycophorin A - Wikipedia

    en.wikipedia.org/wiki/Glycophorin_A

    n/a Ensembl ENSG00000170180 n/a UniProt P02724 n/a RefSeq (mRNA) NM_001308187 NM_001308190 NM_002099 n/a RefSeq (protein) NP_001295116 NP_001295119 NP_002090 n/a Location (UCSC) Chr 4: 144.11 – 144.14 Mb n/a PubMed search n/a Wikidata View/Edit Human Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also recently been ...

  6. Purine nucleotide cycle - Wikipedia

    en.wikipedia.org/wiki/Purine_nucleotide_cycle

    Proteins catabolize into amino acids, and amino acids are precursors for purines, nucleotides and nucleosides which are used in the purine nucleotide cycle. [7] The amino acid glutamate is used to neutralize the ammonia produced when AMP is converted into IMP. Another amino acid, aspartate, is used along with IMP to produce S-AMP in the cycle ...

  7. Stable isotope labeling by amino acids in cell culture

    en.wikipedia.org/wiki/Stable_isotope_labeling_by...

    The NeuCode amino acid method is similar to SILAC but differs in that the labeling only utilizes heavy amino acids. The use of only heavy amino acids eliminates the need for 100% incorporation of amino acids needed for SILAC. The increased multiplexing capability of NeuCode amino acids is from the use of mass defects from extra neutrons in the ...

  8. Scientists Find This Type of Exercise Cuts Heart Disease Risk ...

    www.aol.com/scientists-type-exercise-cuts-heart...

    Walking is a proven means of reducing many of the major risk factors of heart disease, including blood sugar, blood pressure, cholesterol levels, and a high body mass index, Dr. Sagbir continues.

  9. Ergothioneine - Wikipedia

    en.wikipedia.org/wiki/Ergothioneine

    Adaptogenic Antioxidant: Ergothioneine is an adaptogenic antioxidant that preferentially accumulates in cells and tissues exposed to oxidative stress and damage. The organic cation transporter OCTN1 (now known as SLC22A4, a transporter protein with 551 amino acids and three glycosylation sites) in the human body can transport ergothioneine to ...

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