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Research from 2016 looked at women with female pattern hair loss who didn’t respond to 5% minoxidil treatment. The women used 15% minoxidil for 12 weeks. The women used 15% minoxidil for 12 weeks.
Hair loss is part of the natural three-phase hair growth cycle, which involves the anagen (growth) phase, the catagen (declining) phase and the telogen (resting) phase.
Most people affected by hair loss opt for the topical solution or foam versions of minoxidil, with oral minoxidil for hair loss still considered an “off-label” use.
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. [1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.
[27] [28] [29] While used off-label for male pattern hair loss in most of the world, dutasteride is specifically approved for this indication in South Korea and Japan. [30] [31] There is tentative support for spironolactone in women. [14] Due to its feminising side effects and risk of infertility it is not often used by men.
Meanwhile, the effect of minoxidil on hair loss prevention was so clear that in the 1980s physicians were prescribing Loniten off-label to their balding patients. [48] In August 1988, the FDA approved minoxidil for treating baldness in men [48] [52] under the brand name "Rogaine" (FDA rejected Upjohn's first choice, Regain, as misleading [53]).
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