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The earliest recorded artificial induction of immunity in humans was by variolation or inoculation, which is the controlled infection of a subject with a less lethal natural form of smallpox (known as Variola Minor) to make him or her immune to re-infection with the more lethal natural form, Variola Major.
Immunity can be acquired either actively or passively. Immunity is acquired actively when a person is exposed to foreign substances and the immune system responds. Passive immunity is when antibodies are transferred from one host to another. Both actively acquired and passively acquired immunity can be obtained by natural or artificial means.
Inoculation refers to intentionally exposing an individual to a virus, bacterium, other pathogen, or artificial vaccine that may induce active immunity, and inoculation can be done by any suitable route of administration. Many familiar vaccines are injected intramuscularly or swallowed. [citation needed]
Long-term active memory is acquired following infection by activation of B and T cells. Active immunity can also be generated artificially, through vaccination . The principle behind vaccination (also called immunization ) is to introduce an antigen from a pathogen to stimulate the immune system and develop specific immunity against that ...
Active immunization is the induction of immunity after exposure to an antigen. Antibodies are created by the recipient and may be stored permanently. [citation needed]Active immunization can occur naturally when microbes or other antigen are received by a person who has not yet come into contact with the microbes and has no pre-made antibodies for defense.
Active immunization can occur naturally when a person comes in contact with, for example, a microbe. The immune system will eventually create antibodies and other defenses against the microbe. The next time, the immune response against this microbe can be very efficient; this is the case in many of the childhood infections that a person only ...
To enhance the immunity of an individual toward a disease; Can apply to a wide range of diseases; To enhance the immunity of an individual toward a disease; Can apply to a wide range of diseases; Differences For prevention; Mass-produced for a community; Normally produced from an inactivated or killed pathogen of certain bacterial or viral strains
Jenner discovered that inoculating a human with an animal pox virus would grant immunity against smallpox, a disease considered to be one of the most devastating in human history. [ 27 ] [ 28 ] Although the original smallpox vaccine is sometimes considered to be an attenuated vaccine due to its live nature, it was not strictly-speaking ...