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Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome. [5] It is taken by mouth . [ 5 ]
Clomiphene is a selective estrogen receptor modulator (SERM). [5] It is the most widely used fertility drug. [6] Other medications in this class include tamoxifen and raloxifene, although both are not as effective as clomiphene and are thus less widely used for fertility purposes. [7]
In 1931, the first commercially available human chorionic gonadotropin (hCG) was launched, [59] which marked the first emergence of female fertility agents. Subsequently, clomiphene citrate was discovered in 1951, which was then approved by the Food and Drug Administration (FDA) in 1967. [60]
For many parents over the last few decades, fertility drugs and treatments have been the life-changing difference between having a family and not. And at least some of that is thanks to Clomid.
Clomifene citrate (Clomid is a common brand name) is the medication which is most commonly used to treat anovulation. It is a selective estrogen-receptor modulator, affecting the hypothalamic–pituitary–gonadal axis to respond as if there was an estrogen deficit in the body, in effect increasing the production of follicle-stimulating hormone.
In this case, synthetic FSH by injection or Clomid (Clomiphene citrate) via a pill can be given to stimulate follicles to mature in the ovaries. [ citation needed ] Other factors that can affect a woman's chances of conceiving include being overweight or underweight, or her age as female fertility declines after the age of 30.
These treatments can include selective estrogen receptor modulators like clomiphene , a derivative of clomiphene called enclomiphene, or aromatase inhibitors like anastrozole (Arimidex®). These ...
If maintaining fertility is a concern (TRT can lower sperm count), medications including clomiphene citrate, or Clomid, can be used to treat symptoms of low T while protecting against infertility.