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  2. Neutralization (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Neutralization_(chemistry)

    Animation of a strong acid–strong base neutralization titration (using phenolphthalein).The equivalence point is marked in red. In chemistry, neutralization or neutralisation (see spelling differences) is a chemical reaction in which acid and a base react with an equivalent quantity of each other.

  3. Acid–base titration - Wikipedia

    en.wikipedia.org/wiki/Acid–base_titration

    A chemist performing an acid-base titration in lab In the pharmaceutical industry, acid-base titration serves as a fundamental analytical technique with diverse applications. One primary use involves the determination of the concentration of Active Pharmaceutical Ingredients (APIs) in drug formulations, ensuring product quality and compliance ...

  4. Buffer solution - Wikipedia

    en.wikipedia.org/wiki/Buffer_solution

    Similarly, if strong alkali is added to the mixture, the hydrogen ion concentration decreases by less than the amount expected for the quantity of alkali added. In Figure 1, the effect is illustrated by the simulated titration of a weak acid with pK a = 4.7. The relative concentration of undissociated acid is shown in blue, and of its conjugate ...

  5. Titration - Wikipedia

    en.wikipedia.org/wiki/Titration

    Back titration is a titration done in reverse; instead of titrating the original sample, a known excess of standard reagent is added to the solution, and the excess is titrated. A back titration is useful if the endpoint of the reverse titration is easier to identify than the endpoint of the normal titration, as with precipitation reactions

  6. Acid neutralizing capacity - Wikipedia

    en.wikipedia.org/wiki/Acid_neutralizing_capacity

    Acid-neutralizing capacity or ANC in short is a measure for the overall buffering capacity against acidification of a solution, e.g. surface water or soil water.. ANC is defined as the difference between cations of strong bases and anions of strong acids (see below), or dynamically as the amount of acid needed to change the pH value from the sample's value to a chosen different value. [1]

  7. Equivalence point - Wikipedia

    en.wikipedia.org/wiki/Equivalence_point

    A drop of indicator solution is added to the titration at the start; when the color changes the endpoint has been reached, this is an approximation of the equivalence point. Conductance The conductivity of a solution depends on the ions that are present in it. During many titrations, the conductivity changes significantly.

  8. Total acid number - Wikipedia

    en.wikipedia.org/wiki/Total_Acid_Number

    The meter reading (in millivolts) is plotted against the volume of titrant. The end point is taken at the distinct inflection of the resulting titration curve corresponding to the basic buffer solution. Color indicating titration: An appropriate pH color indicator e.g. phenolphthalein, is used. Titrant is added to the sample by means of a burette.

  9. Acid–base reaction - Wikipedia

    en.wikipedia.org/wiki/Acid–base_reaction

    In chemistry, an acid–base reaction is a chemical reaction that occurs between an acid and a base.It can be used to determine pH via titration.Several theoretical frameworks provide alternative conceptions of the reaction mechanisms and their application in solving related problems; these are called the acid–base theories, for example, Brønsted–Lowry acid–base theory.