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The shorter elimination half-life of diphenhydramine (4–8 hours) compared to doxylamine may give it an advantage over doxylamine as a sleep aid in this regard. [27] Antihistamines like doxylamine are sedating initially but tolerance occurs with repeated use and can result in rebound insomnia upon discontinuation. [7] [28]
Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
The list of unapproved chemicals for use as a sleep aid included not only those recommended for banning in 1979, but several others including acetaminophen, aspirin, and passion flower extract. [34] Pharmaceutical manufacturer GlaxoSmithKline owned the Sominex brand in 2011, and announced their decision to divest it in April 2011. [35]
For instance, alcohol and sleep is a tricky combination: a glass or two of red wine can certainly make it easier to fall asleep, but Pavlova says “you end up paying for it the second half of the ...
Older adults are still likely to take a daily, low dose aspirin for the primary prevention of cardiovascular disease, even though doing so carries significant risks. Using aspirin to ward off ...
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