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Congenital insensitivity to pain (CIP), also known as congenital analgesia, is one or more extraordinarily rare conditions in which a person cannot feel (and has never felt) physical pain. [1] The conditions described here are separate from the HSAN group of disorders, which have more specific signs and cause.
Marsili syndrome is an extremely rare genetic disorder which is characterized by symptoms similar to those reported on individuals with congenital insensitivity to pain with anhidrosis. It can be fatal if it goes unnoticed/undiagnosed.
The disease is characterized by the loss of pain sensation mainly in the distal parts of the lower limbs; that is, in the parts of the legs farther away from the center of the body. Since the affected individuals cannot feel pain, minor injuries in this area may not be immediately recognized and may develop into extensive ulcerations.
Since people with this condition are unable to sweat, they are unable to properly regulate their body temperature. [1] Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to lack of protective impulses ...
It has been suggested that multifocal motor neuropathy is distinct from chronic inflammatory demyelinating polyneuropathy and that Lewis-Sumner syndrome is a distinct variant type of chronic inflammatory demyelinating polyneuropathy. [53] The Lewis-Sumner form of this condition is considered a rare disease with only 50 cases reported up to 2004 ...
Cymbiotika Ultimate Pain Balm is the best pain relief cream for sensitive skin due to its powerful blend of natural ingredients and ability to provide fast and targeted relief for pain and discomfort.
Veronica Brown lived with chronic fatigue, depression, and anxiety for over 10 years before she learned they were early signs of Parkinson's disease. Here's how she found relief after diagnosis.
Complex regional pain syndrome is characterized by pain that is distributed regionally, usually starts in an extremity distally, occurs after a trauma, and is disproportionate in severity or duration compared to the expected course of the trauma — the sites affected by complex regional pain syndrome experience autonomic and inflammatory changes.
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