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Goodpasture syndrome (GPS), also known as anti–glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs, glomerulonephritis, [1] and kidney failure. [2]
The pathophysiology of nephritic syndrome is dependent on the underlying disease process, which can vary depending on what condition the nephritic syndrome is secondary to. More specifically, different diseases (many of which are mentioned above in the Causes section) affect different segments of the glomerulus and cause disease-specific ...
Pulmonary-renal syndrome (PRS) is a rare medical syndrome in which respiratory failure involving bleeding in the lungs and kidney failure (glomerulonephritis) occur. [1] PRS is associated with a high rate of morbidity and death. [1] The term was first used by Goodpasture in 1919 to describe the association of respiratory and kidney failure. [1]
Neonatal ichthyosis–sclerosing cholangitis syndrome; Nephritic syndrome; Nephrotic syndrome; Nerve compression syndrome; Netherton syndrome; Neu–Laxova syndrome; Neuro-cardio-facial-cutaneous syndromes; Neurofibromatosis type I; Neuroleptic malignant syndrome; Neuroleptic-Induced Deficit Syndrome; Neutrophil immunodeficiency syndrome; Nevo ...
Similar to other causes of nephrotic syndrome (e.g., focal segmental glomerulosclerosis or minimal change disease), membranous nephropathy is known to predispose affected individuals to develop blood clots such as pulmonary emboli. Membranous nephropathy in particular is known to increase this risk more than other causes of nephrotic syndrome ...
MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults. [3] It should not be confused with membranous glomerulonephritis, a condition in which the basement membrane is thickened, but the mesangium is not.
Budhiraja says that other forms of kidney disease and inflammatory disorders such as glomerulonephritis can also impair kidney function, eventually leading to CKD.
Just like the proteins, these lipids can also get into the urine, causing lipiduria. And those are the hallmarks of nephrotic syndrome—proteinuria, hypoalbuminemia, edema, hyperlipidemia, and lipiduria. Okay so membranoproliferative glomerulonephritis is a type of nephrotic syndrome, got it.