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2. DNA replication - Wikipedia

   en.wikipedia.org/wiki/DNA_replication

   Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.

3. Molecular Structure of Nucleic Acids: A Structure for ...

   en.wikipedia.org/wiki/Molecular_Structure_of...

   DNA replication. The two base-pair complementary chains of the DNA molecule allow replication of the genetic instructions. The "specific pairing" is a key feature of the Watson and Crick model of DNA, the pairing of nucleotide subunits. [5] In DNA, the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. The A:T ...

4. Ribonucleotide - Wikipedia

   en.wikipedia.org/wiki/Ribonucleotide

   DNA is defined by containing 2'-deoxy-ribose nucleic acid while RNA is defined by containing ribose nucleic acid. [1] In some occasions, DNA and RNA may contain some minor bases. Methylated forms of the major bases are most common in DNA. In viral DNA, some bases may be hydroxymethylated or glucosylated.

5. DNA - Wikipedia

   en.wikipedia.org/wiki/DNA

   In DNA replication, DNA-dependent DNA polymerases make copies of DNA polynucleotide chains. To preserve biological information, it is essential that the sequence of bases in each copy are precisely complementary to the sequence of bases in the template strand. Many DNA polymerases have a proofreading activity. Here, the polymerase recognizes ...

6. Eukaryotic DNA replication - Wikipedia

   en.wikipedia.org/wiki/Eukaryotic_DNA_replication

   During DNA replication, the replisome will unwind the parental duplex DNA into a two single-stranded DNA template replication fork in a 5' to 3' direction. The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.

7. DNA polymerase III holoenzyme - Wikipedia

   en.wikipedia.org/wiki/DNA_polymerase_III_holoenzyme

   DNA polymerase III synthesizes base pairs at a rate of around 1000 nucleotides per second. [3] DNA Pol III activity begins after strand separation at the origin of replication. Because DNA synthesis cannot start de novo, an RNA primer, complementary to part of the single-stranded DNA, is synthesized by primase (an RNA polymerase): [citation ...

8. Cell nucleus - Wikipedia

   en.wikipedia.org/wiki/Cell_nucleus

   The main function of the cell nucleus is to control gene expression and mediate the replication of DNA during the cell cycle. [1]: 171 It has been found that replication happens in a localised way in the cell nucleus. In the S phase of interphase of the cell cycle; replication takes place.

9. Directionality (molecular biology) - Wikipedia

   en.wikipedia.org/wiki/Directionality_(molecular...

   Molecular biologists can use nucleotides that lack a 3′-hydroxyl (dideoxyribonucleotides) to interrupt the replication of DNA. This technique is known as the dideoxy chain-termination method or the Sanger method, and is used to determine the order of nucleotides in DNA.