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  2. Methylenetetrahydrofolate reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Methylenetetrahydrofolate...

    MTHFR is the rate-limiting enzyme in the methyl cycle, which includes the conversion of homocysteine into methionine. Defects in variants of MTHFR can therefore lead to hyperhomocysteinemia. [9] There are two common variants of MTHFR deficiency. In the more significant of the two, the individual is homozygous for the 677T polymorphism.

  3. Hypercoagulability in pregnancy - Wikipedia

    en.wikipedia.org/.../Hypercoagulability_in_pregnancy

    Pregnancy-induced hypercoagulability is probably a physiologically adaptive mechanism to prevent post partum hemorrhage. [1] Pregnancy changes the plasma levels of many clotting factors, such as fibrinogen, which can rise up to three times its normal value. [2] Thrombin levels increase. [3] Protein S, an anticoagulant, decreases.

  4. Methylenetetrahydrofolate reductase - Wikipedia

    en.wikipedia.org/wiki/Methylenetetrahydrofolate...

    Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate , a cosubstrate for homocysteine remethylation to methionine .

  5. Christina Perri Speaks Out About Blood-Clotting Diagnosis ...

    www.aol.com/christina-perri-speaks-blood...

    Compounding the pain is the fact that the pregnancy loss in November 2020 came 10 months after she had suffered a miscarriage. "There was so much anger and pain and sadness," she tells People ...

  6. Dysfibrinogenemia - Wikipedia

    en.wikipedia.org/wiki/Dysfibrinogenemia

    This fibrinogen interferes with normal blood clotting and/or lysis of blood clots. The condition therefore may cause pathological bleeding and/or thrombosis . [ 2 ] [ 3 ] [ 4 ] Acquired dysfibrinogenemia is a non-hereditary disorder in which fibrinogen is dysfunctional due to the presence of liver disease , autoimmune disease , a plasma cell ...

  7. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    Thrombophilia can be congenital or acquired. Congenital thrombophilia refers to inborn conditions (and usually hereditary, in which case "hereditary thrombophilia" may be used) that increase the tendency to develop thrombosis, while, on the other hand, acquired thrombophilia refers to conditions that arise later in life.

  8. Antiphospholipid syndrome - Wikipedia

    en.wikipedia.org/wiki/Antiphospholipid_syndrome

    Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.

  9. Gestational thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Gestational_thrombocytopenia

    Gestational (incidental) thrombocytopenia is a condition that commonly affects pregnant women.Thrombocytopenia is defined as the drop in platelet count from the normal range of 150,000–400,000/μL to a count lower than 150,000/μL. [1]