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In patients with CF, one therapy for treating early biofilm development is to employ DNase to structurally weaken the biofilm. [ 4 ] [ 112 ] Biofilm formation of P. aeruginosa , along with other bacteria, is found in 90% of chronic wound infections, which leads to poor healing and high cost of treatment estimated at more than US$25 billion ...
The C2DA inhibit methicillin resistant staphylococcus biofilm, but don't eliminate it. The mechanism of the biofilm inhibition by these molecules is still unknown. C2D is a medium of fatty acid chain that effect on staphylococcus aureus biofilm and dispersion of these biofilm. Pseudomonas aeruginosa is the main source for these molecules. [15]
Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed.Understanding the formation, composition and characteristics of plaque helps in its control. [6]
An experiment was conducted in which researchers compared the efficacy of A. aceti to metformin, a common treatment for patients with type 2 diabetes. The result showed that A. aceti not only increased insulin secretion but also contributed to the repair of damaged pancreatic tissue, showing its potential as a valuable therapeutic method in ...
Chronic periodontitis is initiated by Gram-negative tooth-associated microbial biofilms that elicit a host response, which results in bone and soft tissue destruction. In response to endotoxin derived from periodontal pathogens, several osteoclast-related mediators target the destruction of alveolar bone and supporting connective tissue such as the periodontal ligament.
The new study, conducted in Tainan City, Taiwan, involved 898 people with type 2 diabetes. Of these, 65.1% were taking sulfonylureas, and 41.0% were taking insulin.
Dental caries is a dental biofilm-related oral disease associated with increased consumption of dietary sugar and fermentable carbohydrates. When dental biofilms remain on tooth surfaces, along with frequent exposure to sugars, acidogenic bacteria (members of dental biofilms) will metabolize the sugars to organic acids.
The development of biofilm begins with pellicle formation. Pellicle is an acellular proteinaceous film which covers the teeth. Bacteria colonize on the teeth by adhering to the pellicle-coated surface. Over time, a mature biofilm is formed, creating a cariogenic environment on the tooth surface.