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The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells in anticoagulated whole blood descend in a standardized tube over a period of one hour. It is a common hematology test, and is a non-specific measure of inflammation .
The flat surface of the discoid RBCs gives them a large surface area to make contact with and stick to each other; thus forming a rouleau. They occur when the plasma protein concentration is high, and, because of them, the ESR (erythrocyte sedimentation rate) is also increased. This is a nonspecific indicator of the presence of disease.
Erythrocyte sedimentation rate (ESR) is the rate at which RBCs sink to the bottom (when placed in a vertical column after adding an anticoagulant). Normal values of ESR are: • 3 to 5 mm per hour in males. • 4 to 7 mm per hour in females.
Erythrocyte aggregation is the main determinant of blood viscosity at low shear rate. Rouleaux formation also determines Erythrocyte sedimentation rate which is a non-specific indicator of the presence of disease. [6] Influence of erythrocyte aggregation on in vivo blood flow is still a controversial issue. [7]
One blood test usually performed is the erythrocyte sedimentation rate (ESR) which measures how fast the patient's red blood cells settle in a test tube. The faster the red blood cells settle, the higher the ESR value (measured in mm/hour), which suggests that inflammation may be present.
It correlates with the erythrocyte sedimentation rate (ESR), however not always directly. This is due to the ESR being largely dependent on the elevation of fibrinogen, an acute phase reactant with a half-life of approximately one week. This protein will therefore remain higher for longer despite the removal of the inflammatory stimuli.
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Erythrocyte sedimentation rate (ESR) Male: 0: Age÷2 [154] mm/h: ESR increases with age and tends to be higher in females. [155] Female (Age+10)÷2 [154]