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  2. Chromosomal inversion - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_inversion

    An inversion is a chromosome rearrangement in which a segment of a chromosome becomes inverted within its original position. An inversion occurs when a chromosome undergoes a two breaks within the chromosomal arm, and the segment between the two breaks inserts itself in the opposite direction in the same chromosome arm.

  3. Genetic map function - Wikipedia

    en.wikipedia.org/wiki/Genetic_map_function

    Where d is the distance in map units, the Morgan Mapping Function states that the recombination frequency r can be expressed as =.This assumes that one crossover occurs, at most, in an interval between two loci, and that the probability of the occurrence of this crossover is proportional to the map length of the interval.

  4. Gene conversion - Wikipedia

    en.wikipedia.org/wiki/Gene_conversion

    The Fxy or Mid1 gene in some mammals closely related to house mice (humans, rats, and other Mus species) is located in the sex-linked region of the X chromosome. However, in Mus musculus, it has recently translocated such that the 3’ end of the gene overlaps with the PAR region of the X-chromosome, which is known to be a recombination hotspot ...

  5. Allele frequency - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency

    Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.

  6. Structural variation - Wikipedia

    en.wikipedia.org/wiki/Structural_variation

    Also in this study it's indicated that inversion breakpoints are commonly associated with segmental duplications. [16] One 900 kb inversion in the chromosome 17 is under positive selection and are predicted to increase its frequency in European population. [17]

  7. Cytogenetic notation - Wikipedia

    en.wikipedia.org/wiki/Cytogenetic_notation

    Maternally-derived chromosome rearrangement p: Short arm of a chromosome pat: Paternally-derived chromosome rearrangement psu dic: pseudo dicentric – only one centromere in a dicentric chromosome is active q: Long arm of a chromosome r: Ring chromosome t: Translocation: ter: Terminal end of arm (e.g. 2qter refers to the end of the long arm of ...

  8. Genetic linkage - Wikipedia

    en.wikipedia.org/wiki/Genetic_linkage

    Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.

  9. Coefficient of coincidence - Wikipedia

    en.wikipedia.org/wiki/Coefficient_of_coincidence

    In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. [1] This is called interference.