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Classical cannabinoids are analogs of THC that are based on a dibenzopyran ring. They were developed starting in the 1960s, following the isolation of THC, [50] and were originally the only cannabinoids synthesized. [84] Classical cannabinoids include nabilone and dronabinol, and one of the best known synthetic classical cannabinoids is HU-210 ...
These unprecedented synthetic cannabinoids often feature alphanumeric code names intended to mimic the style of chemical nomenclature used by academic laboratories and pharmaceutical companies, and there is generally little, if any, information available regarding their pharmacology and toxicology at the time of first discovery.
The mixture of cannabinoids produced by a plant is known as the plant's cannabinoid profile. Selective breeding has been used to control the genetics of plants and modify the cannabinoid profile. For example, strains that are used as fiber (commonly called hemp ) are bred such that they are low in psychoactive chemicals like THC.
Pages in category "Cannabinoids" The following 200 pages are in this category, out of approximately 301 total. This list may not reflect recent changes.
List of HU cannabinoids; List of miscellaneous designer cannabinoids; Notes References. This page was last edited on 13 November 2024, at 20:11 (UTC). Text is ...
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [ 1 ] [ 2 ] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis .
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A research group led by Raphael Mechoulam at Hebrew University has synthesized many cannabinoids. Some of those are: HU-210 — a high affinity CB 1 agonist (K i = 0.23 nM) [1] HU-211 — the (+)-enantiomer of HU-210 with dramatically reduced CB 1 affinity [1] HU-239 — also known as ajulemic acid; HU-243; HU-308; HU-320; HU-331; HU-336