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  2. Pyrrole - Wikipedia

    en.wikipedia.org/wiki/Pyrrole

    Pyrrole is an extremely weak base for an amine, with a conjugate acid pK a of −3.8. The most thermodynamically stable pyrrolium cation (C 4 H 6 N +) is formed by protonation at the 2 position. Substitution of pyrrole with alkyl substituents provides a more basic molecule—for example, tetramethylpyrrole has a conjugate acid pK a of +3.7.

  3. Heterocyclic amine - Wikipedia

    en.wikipedia.org/wiki/Heterocyclic_amine

    Nicotine is a molecule containing a pyrrolidine ring attached to a ring of pyridine (other heterocyclic amine). Nicotine belongs to a group of compounds known as alkaloids, which are naturally occurring organic compounds with nitrogen in them. Pyrrole is another compound made up of molecules with a five-membered heterocyclic ring. These ...

  4. Pyrrolizidine alkaloid - Wikipedia

    en.wikipedia.org/wiki/Pyrrolizidine_alkaloid

    A second detoxifying pathway is the formation of the N-oxide [26] [27] In the liver and lungs of certain mammal species enzymes called monooxygenase can prevent aromatization of the double 5-ring and in turn prevent the formation of the pyrrole-protein adduct. [20]

  5. Pyrrolidine - Wikipedia

    en.wikipedia.org/wiki/Pyrrolidine

    Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH 2) 4 NH. It is a cyclic secondary amine , also classified as a saturated heterocycle . It is a colourless liquid that is miscible with water and most organic solvents.

  6. Proline - Wikipedia

    en.wikipedia.org/wiki/Proline

    From a kinetic standpoint, cis–trans proline isomerization is a very slow process that can impede the progress of protein folding by trapping one or more proline residues crucial for folding in the non-native isomer, especially when the native protein requires the cis isomer.

  7. Pyrrolidine alkaloids - Wikipedia

    en.wikipedia.org/wiki/Pyrrolidine_alkaloids

    Alkaloids with partial pyrrolidine structure are usually sub-categorized based on their occurrence and biogenetic origin. Hygrin and cuscohygrin were isolated from the leaves of the coca shrub, [2] while (-)-codonopsinine was isolated from the woodland vine tiger bell.

  8. Tetrapyrrole - Wikipedia

    en.wikipedia.org/wiki/Tetrapyrrole

    Tetrapyrroles are a class of chemical compounds that contain four pyrrole or pyrrole-like rings. The pyrrole/pyrrole derivatives are linked by (= (CH)-or -CH 2-units), in either a linear or a cyclic fashion. Pyrroles are a five-atom ring with four carbon atoms and one nitrogen atom.

  9. Tropane alkaloid - Wikipedia

    en.wikipedia.org/wiki/Tropane_alkaloid

    Chemical structure of tropane which forms the core of tropane alkaloids Chemical structure and phylogeny of tropane alkaloids.Displayed are 3 chemical compounds that occur as natural products in 5 plant species