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  2. Colchicine - Wikipedia

    en.wikipedia.org/wiki/Colchicine

    Colchicine is a medication used to prevent and treat gout, [3] [4] to treat familial Mediterranean fever [5] and Behçet's disease, [6] and to reduce the risk of myocardial infarction. [7] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout.

  3. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.

  4. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    In general, this effect is achieved by action on the proximal tubule of the kidney. Drugs that reduce blood uric acid are not all uricosurics; blood uric acid can be reduced by other mechanisms (see other Antigout Medications). Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints.

  5. Clarithromycin - Wikipedia

    en.wikipedia.org/wiki/Clarithromycin

    Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in people with chronic kidney disease. [9]

  6. Rhabdomyolysis - Wikipedia

    en.wikipedia.org/wiki/Rhabdomyolysis

    In addition to the myoglobinuria, two other mechanisms contribute to kidney impairment: low blood pressure leads to constriction of the blood vessels and therefore a relative lack of blood flow to the kidney, and finally uric acid may form crystals in the tubules of the kidneys, causing obstruction.

  7. AOL Mail for Verizon Customers - AOL Help

    help.aol.com/products/aol-mail-verizon

    AOL Mail welcomes Verizon customers to our safe and delightful email experience!

  8. Fix problems signing into your AOL account - AOL Help

    help.aol.com/articles/help-signing-in

    Use the Sign-in Helper to locate your username and regain access to your account by entering your recovery mobile number or alternate email address.; To manage and recover your account if you forget your password or username, make sure you have access to the recovery phone number or alternate email address you've added to your AOL account.

  9. Talk:Colchicine - Wikipedia

    en.wikipedia.org/wiki/Talk:Colchicine

    I'd like to know more about this, because I've been taking colchicine for 20 years, prescribed for me (0.6mg twice daily, if anyone's interested) after allopurinol turned out to be ineffective for me. The article says not to take colchicine if your kidneys don't work, but so far, knock on wood, that's not one of my medical problems.