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D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link , hence forming a protein dimer .
D-dimer is highly sensitive but not specific (specificity around 50%). In other words, a positive D-dimer is not synonymous with PE, but a negative D-dimer is, with a good degree of certainty, an indication of absence of a PE. [52] A low pretest probability is also valuable in ruling out PE. [53]
More recently, additional risk indicators have been identified, e. g. type 2 allostatic load, [11] high-sensitivity C-reactive protein, d-dimer level, [12] renal failure [13] and altered thyroid function.
Blood clots are dangerous, so you don’t want to ignore an elevated D dimer level. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 ...
It has a sensitivity of 75–100% ... D-dimer. There is an association between the D-dimer blood test and cerebral venous sinus thrombosis. [12]
Dr. Thomas O’Brien and his wife Ruth Reardon O’Brien, the parents of late night comedian Conan O’Brien, have died three days apart. Thomas was 95 and Ruth was 92. The couple were married 66 ...
Principles of D-dimer testing. Fibrin degradation products (FDPs), also known as fibrin split products, are components of the blood produced by clot degeneration. [1] Clotting, also called coagulation, at the wound site produces a mass of fibrin threads called a net that remains in place until the cut is healed. As a cut heals, the clotting ...
'Today' show star Al Roker got honest about aging, and fans are saying he needs to "take care of himself" after seeing his Instagram.