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The drug possess a biological half-life of 14 days when administered by intramuscular injection. [1] Boldenone is a substrate for 5α-reductase and may be converted by this enzyme into 1-testosterone (δ 1 -dihydrotestosterone, δ 1 -DHT, dihydroboldenone) in tissues that express it such as the skin , hair follicles , and prostate gland . [ 6 ]
Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
Biodyl is formulated as a powder to be given in water, and as an injectable solution. The injectable solution is given under the skin, in the muscle, or in a vein, depending on the species of animal. [1] Its intended uses include reducing physiological stress such as due to being transported, and preventing azoturia in performance animals.
In horses, this includes gastric ulcers, [8] right dorsal colitis, [9] and nephrotoxicity. [10] Flunixin is a prohibited substance under International Federation for Equestrian Sports rules, [11] and its use is prohibited or restricted by many other equestrian organizations. At labeled dose (1.1 mg/kg) given IV, detection time was found to be ...
Furosemide is injected either intramuscularly or intravenously, usually 0.5-1.0 mg/kg twice/day, although less before a horse is raced. As with many diuretics, it can cause dehydration and electrolyte imbalance , including loss of potassium , calcium , sodium , and magnesium .
Alcohol is used as a social lubricant, maybe more so as holiday festivities approach. But drinking carries health and other risks. Here are five tips to make it safer.
Equine studies have shown that grapiprant is present in urine 96 hours after the first administration of a dose of 2 mg/kg and has a concentration >0.005 ng/ml. From the excreted dose conducted in horses, it is found that 55%, 15% and 19% of the orally-administered dose was excreted in bile, urine, and faeces respectively. [3]
A Colombian school bus driver has been arrested on rape and kidnapping charges after a girl he allegedly snatched over a decade ago managed to escape, authorities said Thursday.
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