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Molecular breeding is the application of molecular biology tools, often in plant breeding [1] [2] and animal breeding. [3] [4] In the broad sense, molecular breeding can be defined as the use of genetic manipulation performed at the level of DNA to improve traits of interest in plants and animals, and it may also include genetic engineering or gene manipulation, molecular marker-assisted ...
DNA shuffling by molecular breeding was first reported in 1994 by Willem P.C. Stemmer. [1] [7] He started by fragmenting the β-lactamase gene that had been amplified with the polymerase chain reaction (PCR) by using DNase I, which randomly cleaves DNA.
Marker assisted selection or marker aided selection (MAS) is an indirect selection process where a trait of interest is selected based on a marker (morphological, biochemical or DNA/RNA variation) linked to a trait of interest (e.g. productivity, disease resistance, abiotic stress tolerance, and quality), rather than on the trait itself.
GS is a method proposed to address deficiencies of marker-assisted selection (MAS) in breeding programs. However, GS is a form of MAS that differs from it by estimating, at the same time, all genetic markers, haplotypes or marker effects along the entire genome to calculate the values of genomic estimated breeding values (GEBV). [ 1 ]
Critical Reviews in Biochemistry and Molecular Biology; FEBS Journal; FEBS Letters; Journal of Biochemistry; Journal of Biological Chemistry; Journal of Liposome Research; Journal of Structural Biology; Methods in Enzymology; Molecular and Cellular Biochemistry; Proteomes; The Open Clinical Biochemistry Journal; Trends in Biochemistry
[1]: 1 Various techniques were developed to aid in breeding and selection. Hybridization was one way rapid changes in an organism's genetic makeup could be introduced. Crop hybridization most likely first occurred when humans began growing genetically distinct individuals of related species in close proximity.
Molecular Plant is a monthly peer-reviewed scientific journal which publishes both original research and review articles in the field of plant biology, with a particular emphasis on plant cell biology, physiology, biochemistry, molecular biology, genetics, development, plant-microbe interaction, genomics, bioinformatics, and molecular evolution.
Genes to Cells is a peer-reviewed scientific journal that publishes original research on the molecular mechanisms of biological events. The journal has been published since 1996 by Wiley-Blackwell on behalf of the Molecular Biology Society of Japan. [1] [2]