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Dosage and administration [ edit ] Patients are typically given one or two 100,000 I.U. vials of ulinastatin (reconstituted in 100 ml of dextrose 5% or 100 ml of 0.9% normal saline ) by intravenous infusion over the course of one hour, one to three times per day for three to five days.
Diabetics and health care professionals use bolus to refer to a dosage of fast-acting insulin with a meal (as opposed to basal rate, which is a dose of slow-acting insulin or the continuous pumping of a small quantity of fast-acting insulin to cover the glucose output of the liver). [3]
A booster dose is an extra administration of a vaccine after an earlier dose. After initial immunization , a booster provides a re-exposure to the immunizing antigen . It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has declined through time.
Failure to use the pen as instructed may result in medication leakage and administration of a lower dose than was intended. [23] Another administration problem which may impact effectiveness of an injector pen is lipohypertrophy of the subcutaneous tissue near the injection site. For this reason, it is recommended to rotate the injection site ...
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Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...
The need for a booster dose is evaluated in several ways, including the immune response after a booster dose is administered, active B and T cell activity after a certain amount of time that the primary vaccine was given, and prevalence of the disease in vaccinated populations.[2]
This risk is minimized by using proper aseptic technique in preparing the injection and sanitizing the injection site before administration. [9]: 369 Intramuscular injections may also cause an abscess or gangrene at the injection site, depending on the specific medication and amount administered. There is also a risk of nerve or vascular injury ...